“I think our unique contribution has been to use these very high-tech, expensive, state-of-the-art scientific measures to prove how powerful these very low-tech and low-cost interventions can be,” said Ornish, a researcher. professor of medicine at the University of California, San Francisco.
“What’s good for your heart is good for your brain and vice versa,” Ornish said. “Previous studies have shown that moderate lifestyle changes can slow the progression of dementia and Alzheimer’s disease. So my hypothesis is that more intense lifestyle changes can halt or even reverse the decline.”
“It’s low-fat, but that’s only a small part of the overall diet,” Ornish said. “It’s essentially a vegan diet, low in fat and sugar, eating foods that are as close to nature as possible.”
The program also includes one hour a day of yoga-based stress management using stretching, breathing, meditation and relaxation techniques. Strength training and walking or other aerobic exercise are required for 30 minutes a day or an hour three times a week. Smoking is not allowed.
“There are also support groups,” Ornish told CNN, “not just to help people stay on the diet, but to create a safe environment where people can lower their emotional defenses and talk openly and authentically about what’s going on.” is really going on in their lives, warts and all.
“That was the part that surprised me the most — these support groups are really intimate,” he added. “Sharing things like ‘I may look like the perfect dad, but my kids are on heroin’ or whatever. Even with Zoom, they reach the same level of intimacy within one or two sessions because there’s such a hunger for it. .”
Those people are “three to 10 times more likely to get sick and die prematurely from just about anything” compared to people who say they have a sense of love, belonging and community, Ornish claimed.
“Why? Partly because you’re more likely to smoke, overeat, quit exercising and other unhealthy things when you’re feeling lonely and depressed,” Ornish said.
Impact on other chronic diseases
In 1993, insurance giant Mutual of Omaha began reimbursing policyholders for the costs of Ornish’s program, making it the first alternative therapy besides chiropractic to win insurance reimbursement. Medicare began lifestyle interventions for heart disease in 2006.
“And in October 2021, Medicare agreed to cover my heart disease reversal program when it’s done through Zoom, which is really a game changer,” Ornish said. “Now we can reach people at home, in rural areas and food deserts wherever they live, which will help reduce health inequalities and health inequalities.”
“With all this interest in personalized medicine, how come the same lifestyle changes stop and often reverse the progression of such a broad spectrum of the most common and costly chronic diseases?” Ornis asked.
“Because they all share the same underlying biological mechanisms: chronic inflammation, oxidative stress, changes in the microbiome, changes in gene expression, overstimulation of the sympathetic nervous system, changes in immune function, and so on,” he said.
“And in turn, each of these is directly affected by what we eat, how we respond to stress, how much exercise we get, and how much love and support we have,” Ornish said.
“After just three months on the Ornish life program, the research found a number of genes that regulate or prevent disease, and genes that drive many of the mechanisms that cause all of these different conditions, have been turned off,” Ornish said.
“You don’t technically change your genes, but you change the expression of those genes with chemical switches, turning them on or off,” he said. “So that means it’s no longer all in our genes, making us victims of our genetic fate. We’re not victims. There’s a lot we can do.”
“We found that telomerase, the enzyme that repairs and lengthens telomeres, increased by 30% after just three months on the program,” Ornish said. “Then we found that people who had been on the program for five years had telomeres that were about 10% longer, a sign that aging is being reversed at the cellular level.”
Will the same lifestyle interventions be enough to slow or even reverse cognitive decline in Alzheimer’s disease and other dementias? Time will tell. Ornish’s research is still ongoing and while preliminary results appear promising, all data must be collected, analyzed and peer-reviewed before a result can be reported.
“But I believe it’s not one diet and lifestyle intervention for heart disease, another for diabetes or prostate cancer, and yet another for Alzheimer’s disease. It’s really the same for all these different conditions,” Ornish told CNN.
“To reverse the disease, you have to follow the interventions almost 100%. If you just try to prevent disease, the more you change, the more you improve. But the most important thing is your overall way of eating, living and loving, so that we can all die young and as old as possible.”